‘Daraprim’ Resistance in Experimental Malarial Infections
نویسندگان
چکیده
منابع مشابه
Experimental Inoculation of Malarial Fever
were found, we see that the fever came on in one case 22 days after the first bite, and in the other about 15 days after the first bite. It may be said by those who are opposed to the mosquito theory that the fact that the attacks of fever came after the mosquito bites was entirely accidental. This was the objection raised against the cases which were experimented on in Italy. We have carefully...
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1. The malarial parasite is extracellular throughout its life cycle and migrates from red corpuscle to red corpuscle destroying each before it abandons it; in the brief intervals between, the parasite is free in the blood serum; it does not remain long free, but almost immediately attaches itself to another red corpuscle by means of delicate pseudopodia. 2. The compact form of the tertian paras...
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The ability of four 9,10-dihydroethanoanthracene derivatives (BG920, BG932, BG958, and BG996), as well as verapamil and promethazine, to reverse chloroquine resistance was assessed against 24 chloroquine-resistant and 10 chloroquine-susceptible strains of Plasmodium falciparum from different countries. The 9,10-dihydroethanoanthracene derivatives clearly increase chloroquine susceptibility only...
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In India, the first confirmed report of chloroquine resistance in P. falciparum was reported in 1973. Since then there has been a rise in resistance to chloroquine in Plasmodium falciparum and vivax as also to pyrimethamine sulphadoxine group of drugs. Resistance to artemisinin and its derivatives has not been documented in India except for isolated case reports. In a multicentric study of arte...
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ALTHOUGH toxoplasmosis was suggested as a cause of congenital choroidoretinitis over 30 years ago, the definite importance of the organism in the acquired disease is still in doubt. The early observations of Janku (1923) and Torres (1927) attracted little attention until Wolf and Cowen (1937) isolated the parasite from a fatal human case. The frequent occurrence of retinitis in the neonatal cas...
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ژورنال
عنوان ژورنال: Nature
سال: 1952
ISSN: 0028-0836,1476-4687
DOI: 10.1038/170415a0